Corticosteroid therapy for the management of paradoxical inflammatory reaction in patients with pulmonary tuberculosis

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[Clinical analysis of pulmonary tuberculosis in association with corticosteroid therapy].

In the last five years, five patients (three males and two females) among a total of 162 patients (3.1%) ranging from 63 to 79 years old developed pulmonary tuberculosis during the long-term corticosteroid therapy. The underlying diseases of these cases were pulmonary fibrosis in two, polyarteritis nodosa in one, RPGN + pulmonary bleeding in one, and mycosis fungoides in one. The total corticos...

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Paradoxical upgrading reaction in extra-pulmonary tuberculosis: association with vitamin D therapy

SETTING Glasgow, Scotland, UK. BACKGROUND Paradoxical reactions in tuberculosis (TB) are a notable example of our incomplete understanding of host-pathogen interactions during anti-tuberculosis treatment. OBJECTIVES To determine risk factors for a TB paradoxical reaction, and specifically to assess for an independent association with vitamin D use. DESIGN Consecutive human immunodeficienc...

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Inflammatory paradoxical reaction occurring in tuberculosis patients treated with HAART and rifampicin.

The introduction of highly active antiretroviral treatment (HAART) during tuberculosis treatment may be followed by a systemic inflammatory and paradoxical reaction with flare of symptoms and lymph node enlargement. This reaction has also been observed in association with the treatment of disseminated Mycobacterium avium complex (MAC) infection, Cytomegalovirus and other opportunistic infection...

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Tuberculosis paradoxical reaction.

T is endemic in this part of the world. We frequently encounter patients with both pulmonary and extrapulmonary tuberculosis regardless of whether they are infected with human immunodeficiency virus (HIV) or not. It is not uncommon for physicians to see clinical or radiological, or both, worsening of the disease while their patient is on anti-tuberculous treatment, the so-called paradoxical rea...

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ژورنال

عنوان ژورنال: Infection

سال: 2020

ISSN: 0300-8126,1439-0973

DOI: 10.1007/s15010-020-01430-7